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It is not wise to go to sleep with mascara on. It can cause a bacterial infection and depending on the thickness of the mascara it can get into your eye and cause red, swollen eyes in the morning, not to mention the fact that you may wake up with raccoon eyes. A simple "in a hurry" way to remove mascara before going to sleep is to use facial cleansing wipes to remove as much mascara as possible. Still, nothing comes close to keeping lashes in condition by removing all makeup before going to sleep.