Co-enzyme Q10 has two important roles: it is an essential part of the cellular respiration system located in the mitochondria, and it is an antioxidant. CoQ10 improves both the rate and efficiency of energy production in the cells, including the skin and at the same time protects mitochondria from free radicals. CoQ10 is sometimes called a "biomarker of aging" because its level correlates so well with aging.

In most people over thirty, levels of CoQ10 in the skin is below optimum, resulting in a lesser ability to produce collagen, elastin and other important skin molecules. CoQ10-depleted skin may also be more prone to the damage by free radicals, which are particularly abundant with exposure of the skin to the elements. Thus, CoQ10 may boost skin repair and regeneration. Furthermore, CoQ10 is a small molecule that can relatively easily penetrate into skin cells.

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